Press Release Summary = Apoptosis, a programmed, cell-autonomous death process, plays important roles in a variety of physiological and pathological events (1).
Press Release Body = These range from normal fetal development to diseases, such as cancer (2), organ failure and neurodegenerative diseases. During apoptosis, caspases execute the disassembly of cellular components by proteolytic cleavage of a variety of substrates, such as poly-(ADP ribose) polymerase (3), DNA-dependent protein kinase (DNA-PK), topoisomerases, and protein kinase C delta (4). At least ten caspases have been discovered. Some of these caspases identify and cleave a specific peptide substrate, while others recognize the same peptide substrate (4).
AnaSpec's line of EnzoLyteT Caspase Assay Kits are optimized for high-throughput screening. HTS-optimized features include: one-step homogeneous assays, a convenient mix-and-read format, and highly sensitive fluorimetric components.
EnzoLyteT Homogeneous Caspase-3/7 Assay Kits - For detecting caspase 3/7 activity in cells and/or for screening caspase 3/7 inducers or inhibitors - Measures activity directly in 96- or 384-well microplate, bifunctional lysis buffer lyses cells as well as provides optimal buffer condition for caspase 3/7 activity
EnzoLyteT Homogeneous AFC Caspase-3/7 Assay Kit · 500 assays in 96-well format · Ex/Em(nm)
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2022
